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His team found, surprisingly, that histone H3.3 seems to have its own set of chaperone proteins that place it, and it alone, into the genome4, 5. The chaperone proteins for histone H3.3 had not previously been identified as chromatin remodelers, but researchers in other laboratories had implicated these proteins in mental retardation, cell death and pancreatic cancer..
At the time of its release several weeks ago, with Clinton leading heavily in many polls, Moore was accused of alarmism and opportunism tweets during the New York premiere elicited allegations of both. But the director said that he was simply observing behavior in his native Midwest and had no interest other than to call it like he saw it..
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